Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6135632

CCCOC1CCNCC1.O=C(O)C(F)(F)F

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 5/20 0.34
ITGA2B P08514 5/20 0.34
FUCA1 P04066 1/20 0.34
HRH4 Q9H3N8 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
CES2 O00748 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
TSHR P16473 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
GABRA4 P48169 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6134977 0.91 ITGB3 (0.39) ITGB3ITGA2BFUCA1SLC6A2SLC6A4
Trifluoroacetic Acid SCHEMBL6134245 0.87 GABRP (0.35) FUCA1HRH4HRH3SLC6A2SLC6A4
Trifluoroacetic Acid SCHEMBL23466733 0.86 CHRNB2 (0.38) HRH4HRH3SLC6A2SLC6A4GABRP
Trifluoroacetic Acid SCHEMBL4010515 0.83 SLC6A2 (0.33) HRH4HRH3SLC6A2SLC6A4GABRP
SCHEMBL2149346 0.82 SLC6A2 (0.36) SLC6A2SLC6A4
Trifluoroacetic Acid SCHEMBL6135130 0.81 SLC6A2 (0.34) ITGB3ITGA2BHRH4HRH3SLC6A2
Hydrochloric Acid SCHEMBL1223342 0.80 GNAO1 (0.37) SLC6A2SLC6A4
Trifluoroacetic Acid SCHEMBL4012459 0.80 PDK2 (0.34) ITGB3ITGA2BHRH4HRH3GABRP
Trifluoroacetic Acid SCHEMBL2912962 0.78 GABRP (0.39) FUCA1HRH4HRH3SLC6A2SLC6A4
Trifluoroacetic Acid SCHEMBL27730437 0.76 EPHX2 (0.36) HRH4HRH3SLC6A2SLC6A4GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050261177-A1 Compound ASTELLAS PHARMA INC. (JP) 2005-11-24 US disclosed
EP-1366066-A2 CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-12-03 EP disclosed
WO-2002072621-A2 CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261177-A1 Compound MANBA, MAN2B1, MAN2A1 ITGB3 1732/4885ITGA2B 3776/4885FUCA1 302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.