Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6135130

CC(C)CCCOC1CCNCC1.O=C(O)C(F)(F)F

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 12/20 0.34
SLC6A4 P31645 12/20 0.34
SLC6A3 Q01959 4/20 0.33
ITGB3 P05106 5/20 0.32
ITGA2B P08514 5/20 0.32
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP7 Q9UHL4 1/20 0.32
HRH4 Q9H3N8 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL6134977 0.84 ITGB3 (0.39) SLC6A2SLC6A4ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL6135632 0.81 ITGB3 (0.34) SLC6A2SLC6A4ITGB3ITGA2BHRH4
Trifluoroacetic Acid SCHEMBL23466733 0.80 CHRNB2 (0.38) SLC6A2SLC6A4HRH4HRH3
Trifluoroacetic Acid SCHEMBL6134245 0.77 GABRP (0.35) SLC6A2SLC6A4SLC6A3HRH4HRH3
Trifluoroacetic Acid SCHEMBL4010515 0.77 SLC6A2 (0.33) SLC6A2SLC6A4HRH4HRH3
SCHEMBL12329129 0.76 CHRM1 (0.36) SLC6A2SLC6A4SLC6A3
SCHEMBL3793194 0.75 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL20577161 0.74 SLC6A1 (0.33) SLC6A2SLC6A4SLC6A3HRH4HRH3
SCHEMBL6135131 0.74 LIPC (0.34)
Trifluoroacetic Acid SCHEMBL2912962 0.72 GABRP (0.39) SLC6A2SLC6A4HRH4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050261177-A1 Compound ASTELLAS PHARMA INC. (JP) 2005-11-24 US disclosed
EP-1366066-A2 CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-12-03 EP disclosed
WO-2002072621-A2 CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261177-A1 Compound MANBA, MAN2B1, MAN2A1 SLC6A2 4745/4885SLC6A4 4708/4885SLC6A3 4464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.