Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136228 | 0.94 | HDAC3 (0.58) | L3MBTL1KMT2AMEN1HDAC3HDAC1 | |
| SCHEMBL6136444 | 0.94 | LMNA (0.54) | L3MBTL1KMT2AMEN1KDM4EPOLB | |
| SCHEMBL6136381 | 0.84 | BCHE (0.64) | KMT2ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9832305 | 0.82 | ALDH1A1 (0.56) | KMT2AMEN1KDM4ELMNAALDH1A1 | |
| SCHEMBL4655867 | 0.80 | ALDH1A1 (0.57) | L3MBTL1KMT2AMEN1HDAC3HDAC1 | |
| SCHEMBL16839736 | 0.79 | LTA4H (0.60) | KMT2AMEN1POLB | |
| SCHEMBL9832496 | 0.79 | KDM4E (0.58) | L3MBTL1KMT2AMEN1HDAC3HDAC1 | |
| SCHEMBL5685284 | 0.78 | CALM1 (0.57) | KMT2AHDAC1HDAC2SMN1; SMN2LMNA | |
| SCHEMBL3187109 | 0.77 | KDM4E (0.64) | L3MBTL1KMT2AMEN1HDAC3HDAC1 | |
| SCHEMBL9830258 | 0.77 | MEN1 (0.61) | KMT2AMEN1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042279-B1 | SUBSTITUTED BETA-ALANINES | AVENTIS PHARMA LTD (GB) | 2005-03-02 | — | — | EP | disclosed |
| US-6352977-B1 | ALANINE WITH PRODRUGS | AVENTIS PHARMA LIMITED (GB) | 2002-03-05 | — | — | US | disclosed |
| EP-1042279-A1 | SUBSTITUTED BETA-ALANINES | Aventis Pharma Limited (GB) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033789-A1 | SUBSTITUTED β-ALANINES | AVENTIS PHARMA LIMITED (GB) | 1999-07-08 | — | — | WO | disclosed |