Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136380 | 0.94 | L3MBTL1 (0.61) | LMNAL3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL6136228 | 0.86 | HDAC3 (0.58) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL6136381 | 0.82 | BCHE (0.64) | LMNASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL7772808 | 0.82 | LMNA (0.63) | LMNAL3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL16839736 | 0.82 | LTA4H (0.60) | KMT2AMEN1LTA4HPOLB | |
| SCHEMBL2848440 | 0.81 | CYP4F2 (0.59) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL5940295 | 0.80 | LTA4H (0.50) | S1PR1SMN1; SMN2ALDH1A1KMT2ALTA4H | |
| SCHEMBL16839772 | 0.80 | SMN1; SMN2 (0.51) | LMNAL3MBTL1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL16839712 | 0.80 | SMN1; SMN2 (0.62) | LMNASMN1; SMN2ALDH1A1LTA4HKDM4E | |
| SCHEMBL16839029 | 0.79 | S1PR2 (0.44) | S1PR2S1PR1S1PR3LPAR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042279-B1 | SUBSTITUTED BETA-ALANINES | AVENTIS PHARMA LTD (GB) | 2005-03-02 | — | — | EP | disclosed |
| CN-1163477-C | Substituted beta-alanines | — | 2004-08-25 | — | — | CN | disclosed |
| US-6352977-B1 | ALANINE WITH PRODRUGS | AVENTIS PHARMA LIMITED (GB) | 2002-03-05 | — | — | US | disclosed |
| CN-1283181-A | Substituted beta-alanines | AWONGTISFAMA CO LTD (GB) | 2001-02-07 | — | — | CN | disclosed |
| EP-1042279-A1 | SUBSTITUTED BETA-ALANINES | Aventis Pharma Limited (GB) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033789-A1 | SUBSTITUTED β-ALANINES | AVENTIS PHARMA LIMITED (GB) | 1999-07-08 | — | — | WO | disclosed |