Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.48 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | GRN | P28799 | 4/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424709 | 0.86 | TAS1R3 (0.52) | CNR2CCKBRCA2HDAC2 | |
| SCHEMBL4056322 | 0.83 | CNR2 (0.50) | CNR2NOD1 | |
| SCHEMBL6349086 | 0.82 | CNR2 (0.73) | CNR2NOD1MMEPOLBKMT2A | |
| SCHEMBL6793460 | 0.82 | CNR2 (0.50) | CNR2NOD1CCKBRGRNSORT1 | |
| SCHEMBL9354646 | 0.80 | CNR2 (0.57) | CNR2NOD1CA2MMEPOLB | |
| SCHEMBL4060569 | 0.78 | POLB (0.52) | CNR2POLBKMT2AITGB1ITGA4 | |
| SCHEMBL6136711 | 0.77 | THRA (0.46) | CNR2CCKBRGRNSORT1POLB | |
| SCHEMBL6136706 | 0.77 | THRA (0.46) | CNR2CCKBRGRNSORT1POLB | |
| SCHEMBL31661673 | 0.77 | CNR2 (0.72) | CNR2NOD1POLBKMT2AITGB1 | |
| SCHEMBL10354480 | 0.76 | GPR34 (0.55) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951464-B1 | N-(ARYL/HETEROARYLACETYL) AMINO ACID ESTERS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | ELAN PHARM INC (US) | 2005-05-11 | — | — | EP | claimed |