Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | GRN | P28799 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136678 | 0.86 | S1PR3 (0.48) | CA2CA1S1PR3GRNSORT1 | |
| SCHEMBL6136584 | 0.82 | CNR2 (0.50) | CNR2CA2NOD1ITGB1ITGA4 | |
| SCHEMBL9354646 | 0.82 | CNR2 (0.57) | CNR2CA2NOD1ITGB1ITGA4 | |
| SCHEMBL6349086 | 0.82 | CNR2 (0.73) | CNR2NOD1MEN1KMT2AMME | |
| SCHEMBL6136504 | 0.79 | L3MBTL1 (0.49) | CA2CA1S1PR3GRNSORT1 | |
| SCHEMBL6136500 | 0.79 | L3MBTL1 (0.49) | CA2CA1S1PR3GRNSORT1 | |
| SCHEMBL8599743 | 0.79 | CA2 (0.46) | CA2CA1S1PR3L3MBTL1MEN1 | |
| SCHEMBL9647871 | 0.77 | CCKBR (0.73) | LMNACCKBR | |
| SCHEMBL9647866 | 0.77 | CCKBR (0.73) | LMNACCKBR | |
| SCHEMBL4056322 | 0.77 | CNR2 (0.50) | CNR2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825354-B2 | OSTEOPOROSIS; RHEUMATIC DISEASES | WYETH HOLDINGS CORPORATION | 2004-11-30 | — | — | US | disclosed |