⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137027 | 1.00 | — | — | |
| SCHEMBL6136581 | 0.76 | — | — | |
| SCHEMBL7974207 | 0.76 | RXRA (0.41) | — | |
| SCHEMBL7962818 | 0.68 | EPHX2 (0.38) | — | |
| SCHEMBL9034843 | 0.67 | MEN1 (0.38) | — | |
| SCHEMBL6703350 | 0.65 | ENPP2 (0.40) | — | |
| SCHEMBL6700681 | 0.65 | ENPP2 (0.40) | — | |
| SCHEMBL5240366 | 0.65 | KCNN4 (0.31) | — | |
| SCHEMBL3827052 | 0.65 | KCNN4 (0.33) | — | |
| SCHEMBL5738210 | 0.65 | ADORA2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313470-A4 | NOVEL ALICYCLIC IMIDAZOLES AS H 3 AGENTS | GLIATECH INC (US) | 2005-02-16 | — | — | EP | disclosed |
| EP-1313470-A1 | NOVEL ALICYCLIC IMIDAZOLES AS H 3 AGENTS | GLIATECH, INC. (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002013821-A1 | NOVEL ALICYCLIC IMIDAZOLES AS H3 AGENTS | GLIATECH, INC. (US) | 2002-02-21 | — | — | WO | disclosed |