Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974207 | 0.82 | RXRA (0.41) | EPHX2 | |
| SCHEMBL18065068 | 0.74 | TRPM8 (0.36) | — | |
| SCHEMBL6136581 | 0.73 | — | — | |
| SCHEMBL7796073 | 0.72 | SIRT2 (0.39) | EPHX2MCL1BCL2APP | |
| SCHEMBL17146213 | 0.71 | MCL1 (0.55) | EPHX2MCL1BCL2APPTRPM5 | |
| SCHEMBL15208924 | 0.71 | MCL1 (0.55) | EPHX2MCL1BCL2APPTRPM5 | |
| SCHEMBL13929891 | 0.71 | MCL1 (0.55) | EPHX2MCL1BCL2APPTRPM5 | |
| SCHEMBL17590033 | 0.71 | MCL1 (0.55) | EPHX2MCL1BCL2APPTRPM5 | |
| SCHEMBL7974225 | 0.71 | APP (0.36) | EPHX2APP | |
| SCHEMBL20640587 | 0.71 | GPR88 (0.47) | GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081317-A1 | CHIRAL IMIDAZOYL INTERMEDIATES FOR THE SYNTHESIS OF 2-(4-IMIDAZOYL)-CYCLOPROPYL DERIVATIVES | GLIATECH, INC. (US) | 2001-11-01 | — | — | WO | disclosed |