Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5421340 | 0.82 | MYC (0.47) | DHODHLMNATP53POLB | |
| SCHEMBL5416536 | 0.75 | L3MBTL1 (0.54) | DHODHTP53POLB | |
| SCHEMBL5410404 | 0.73 | DHODH (0.39) | DHODH | |
| SCHEMBL9134337 | 0.73 | HPD (0.64) | HPDLMNAPOLB | |
| SCHEMBL5420508 | 0.71 | CTSK (0.47) | — | |
| SCHEMBL7507573 | 0.70 | DHODH (0.38) | DHODHLMNA | |
| SCHEMBL8176844 | 0.69 | F9 (0.41) | LMNA | |
| SCHEMBL10191434 | 0.69 | HPGD (0.50) | HPD | |
| SCHEMBL7344969 | 0.69 | TSHR (0.50) | HPD | |
| SCHEMBL20917012 | 0.67 | HPD (0.47) | HPDTP53TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100789-B1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER CROPSCIENCE AG (DE) | 2005-02-09 | — | — | EP | disclosed |
| CN-1310714-A | Substituted Benzoylcyclohexanediones | BAYER AG (DE) | 2001-08-29 | — | — | CN | disclosed |
| EP-1100789-A1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER AG (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000005221-A1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-03 | — | — | WO | disclosed |