Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139870 | 0.86 | L3MBTL1 (0.52) | L3MBTL1TDP1KMT2AMEN1PARP10 | |
| SCHEMBL6137828 | 0.81 | ACHE (0.56) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL14027622 | 0.78 | TDP1 (0.51) | L3MBTL1TDP1KMT2ANPC1RAB9A | |
| SCHEMBL17583595 | 0.74 | L3MBTL1 (0.70) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9695219 | 0.74 | ACHE (0.70) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6137598 | 0.73 | DRD2 (0.53) | L3MBTL1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6137921 | 0.71 | KDM4E (0.45) | ALDH1A1PARP10NPC1RAB9AMTNR1A | |
| SCHEMBL6003647 | 0.71 | LPAR1 (0.53) | L3MBTL1TDP1KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8767719 | 0.71 | CA1 (0.45) | KMT2AMEN1MAPTPARP10HDAC1 | |
| SCHEMBL6138031 | 0.71 | CA1 (0.45) | KMT2AMEN1ALDH1A1PARP10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032556-A4 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE INC (US) | 2005-02-02 | — | — | EP | claimed |
| EP-1032556-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999020599-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-04-29 | — | — | WO | claimed |