Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137828 | 0.79 | ACHE (0.56) | KDM4EHPGDALDH1A1HTTLPAR1 | |
| SCHEMBL6137598 | 0.78 | DRD2 (0.53) | KDM4EHPGDALDH1A1DRD2DRD3 | |
| SCHEMBL6003647 | 0.74 | LPAR1 (0.53) | KDM4EHPGDALDH1A1HTTLPAR1 | |
| SCHEMBL4627482 | 0.73 | SCN2A (0.59) | KDM4EALDH1A1CRHBPCRHR2HTT | |
| SCHEMBL6137845 | 0.71 | L3MBTL1 (0.52) | KDM4EHPGDMTNR1AALDH1A1PARP10 | |
| SCHEMBL6138031 | 0.71 | CA1 (0.45) | KDM4EHPGDCES2CES1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8767719 | 0.71 | CA1 (0.45) | KDM4EHPGDCES2CES1DRD2 | |
| SCHEMBL28183213 | 0.67 | CES2 (0.65) | KDM4EHPGDCES2CES1ALDH1A1 | |
| SCHEMBL6137840 | 0.67 | SCN5A (0.49) | PRSS1PRSS2PRSS3PARP10NPC1 | |
| Anisole SCHEMBL27279235 | 0.66 | CA4 (0.58) | CES2CES1ALDH1A1HTTPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032556-A4 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE INC (US) | 2005-02-02 | — | — | EP | claimed |
| EP-1032556-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999020599-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-04-29 | — | — | WO | claimed |