Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.55 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | GLS | O94925 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18493707 | 0.87 | PIN1 (0.56) | HDAC2HDAC8HDAC6PIN1HDAC1 | |
| SCHEMBL16359253 | 0.87 | HDAC2 (0.53) | HDAC2HDAC8HDAC6PIN1HDAC1 | |
| SCHEMBL24533898 | 0.87 | PIN1 (0.59) | HDAC2HDAC8HDAC6PIN1HDAC1 | |
| SCHEMBL5458748 | 0.87 | ITGB3 (0.65) | HDAC2HDAC8HDAC6PIN1MME | |
| SCHEMBL4153101 | 0.87 | ITGB3 (0.65) | HDAC2HDAC8HDAC6PIN1MME | |
| SCHEMBL4153095 | 0.87 | ITGB3 (0.65) | HDAC2HDAC8HDAC6PIN1MME | |
| SCHEMBL29637713 | 0.85 | SMN1; SMN2 (0.57) | HDAC2HDAC8HDAC6PIN1HDAC1 | |
| SCHEMBL22361824 | 0.85 | MAPT (0.56) | HDAC2HDAC8HDAC6PIN1HDAC1 | |
| SCHEMBL30468579 | 0.85 | FNTA (0.58) | HDAC2HDAC8HDAC6PIN1FNTA | |
| SCHEMBL19418905 | 0.85 | MAPT (0.56) | HDAC2HDAC8HDAC6PIN1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047391-A4 | ALPHA-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS | GILLETTE CO (US) | 2005-01-19 | — | — | EP | claimed |
| US-6238655-B1 | USEFUL IN THE FORMULATION OF DEODORANTS, ANTIPERSPIRANTS, BODY SPRAYS, AND OTHER SKIN TREATMENT COMPOSITIONS. | THE GILLETTE COMPANY | 2001-05-29 | — | — | US | claimed |
| EP-1047391-A1 | ALPHA-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS | THE GILLETTE COMPANY (US) | 2000-11-02 | — | — | EP | claimed |
| WO-1999030679-A1 | α-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS | THE GILLETTE COMPANY (US) | 1999-06-24 | — | — | WO | claimed |
| US-10363237-B2 | Compositions and methods of inhibiting N-acylethanolamine-hydrolyzing acid amidase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-07-30 | — | — | US | disclosed |
| EP-1047391-A4 | ALPHA-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS | GILLETTE CO (US) | 2005-01-19 | — | — | EP | disclosed |
| US-6238655-B1 | USEFUL IN THE FORMULATION OF DEODORANTS, ANTIPERSPIRANTS, BODY SPRAYS, AND OTHER SKIN TREATMENT COMPOSITIONS. | THE GILLETTE COMPANY | 2001-05-29 | — | — | US | disclosed |
| EP-1047391-A1 | ALPHA-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS | THE GILLETTE COMPANY (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999030679-A1 | α-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS | THE GILLETTE COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10363237-B2 | Compositions and methods of inhibiting N-acylethanolamine-hydrolyzing acid amidase | NAAA, NAPEPLD, FAAH | HDAC2 342/4885HDAC8 288/4885HDAC6 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.