Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673266 | 0.86 | KDM4E (0.41) | MAPK1FLT1FLT4KDRKDM4E | |
| SCHEMBL7492506 | 0.86 | KDM4E (0.41) | MAPK1FLT1FLT4KDRKDM4E | |
| SCHEMBL6139230 | 0.84 | PSEN1 (0.43) | FLT1FLT4KDRKDM4EALDH1A1 | |
| SCHEMBL28824902 | 0.84 | PSEN1 (0.43) | FLT1FLT4KDRKDM4EALDH1A1 | |
| SCHEMBL2169427 | 0.81 | ABCB11 (0.39) | MAPTALDH1A1ABCB11 | |
| SCHEMBL28560399 | 0.81 | ABCB11 (0.39) | MAPTALDH1A1ABCB11 | |
| SCHEMBL26301826 | 0.81 | ABCB11 (0.39) | MAPTALDH1A1ABCB11 | |
| SCHEMBL6139499 | 0.78 | EPHX2 (0.39) | MAPTALDH1A1RAB9AHTTABCB11 | |
| SCHEMBL28046418 | 0.78 | ALDH1A1 (0.51) | MAPTALDH1A1L3MBTL1HPGD | |
| SCHEMBL28555501 | 0.78 | LMNA (0.42) | KDM4EMAPTALDH1A1HTTABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894186-B2 | Hydroxyacetic ester derivatives, preparation method and use as synthesis intermediates | SANOFI-SYNTHELABO (FR) | 2005-05-17 | — | — | US | claimed |