Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670976 | 0.88 | KEAP1 (0.41) | EPHX2LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7494636 | 0.88 | KEAP1 (0.41) | EPHX2LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28555501 | 0.82 | LMNA (0.42) | LMNAMEN1KMT2AMAPTHTT | |
| SCHEMBL6139065 | 0.81 | ENPP3 (0.43) | EPHX2ABCB11GAA | |
| SCHEMBL2169427 | 0.81 | ABCB11 (0.39) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL26301826 | 0.81 | ABCB11 (0.39) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL28560399 | 0.81 | ABCB11 (0.39) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL28824902 | 0.79 | PSEN1 (0.43) | LMNAMEN1KMT2AABCB11ALDH1A1 | |
| SCHEMBL6139230 | 0.79 | PSEN1 (0.43) | LMNAMEN1KMT2AABCB11ALDH1A1 | |
| SCHEMBL6138912 | 0.78 | MAPK1 (0.39) | MAPTHTTABCB11ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894186-B2 | Hydroxyacetic ester derivatives, preparation method and use as synthesis intermediates | SANOFI-SYNTHELABO (FR) | 2005-05-17 | — | — | US | claimed |