Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.50 |
| ▸ | GABRP | O00591 | 3/20 | 0.50 |
| ▸ | GABRD | O14764 | 3/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.50 |
| ▸ | GABRE | P78334 | 3/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049347 | 0.84 | GABRA1 (0.44) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL6138810 | 0.82 | GABRA1 (0.44) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL23622949 | 0.78 | PRKAB2 (0.63) | GABRA1GABRB2F7F3PRKAB2 | |
| SCHEMBL17337966 | 0.76 | GABRA1 (0.67) | GABRA1GABRB2 | |
| SCHEMBL1081795 | 0.75 | F7 (0.66) | F7F3 | |
| SCHEMBL17337938 | 0.75 | HTR1A (0.54) | GABRA1GABRB2 | |
| SCHEMBL17337999 | 0.74 | GABRA1 (0.68) | GABRA1GABRB2 | |
| SCHEMBL6139977 | 0.74 | SMAD3 (0.58) | HDAC6F7F3MGLL | |
| SCHEMBL15902273 | 0.73 | GABRA1 (0.55) | GABRA1GABRB2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL21002079 | 0.73 | MGLL (0.68) | HDAC6MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311477-A4 | NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORP (KR) | 2005-01-12 | — | — | EP | disclosed |
| EP-1311477-A1 | NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002016317-A1 | NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2002-02-28 | — | — | WO | disclosed |