SCHEMBL6140146

SCHEMBL6140146

CC(C)(C)OC(=O)COc1cccc([S+](c2cccc(OCC(=O)OC(C)(C)C)c2)c2ccccn2)c1.Cc1ccc(S(=O)(=O)[O-])c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
RAPGEF3 O95398 1/20 0.39
KDM4E B2RXH2 3/20 0.37
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
GAA P10253 2/20 0.35
ALDH1A1 P00352 1/20 0.35
F2 P00734 2/20 0.34
KMT2A Q03164 1/20 0.34
PTPN1 P18031 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140516 0.90 RAPGEF3 (0.39) MAPTSMN1; SMN2RAPGEF3KDM4ENPC1
SCHEMBL6140422 0.87 KMT2A (0.39) MAPTSMN1; SMN2RAPGEF3KDM4ENPC1
SCHEMBL6140432 0.83 RORC (0.40) MAPTSMN1; SMN2RAPGEF3KDM4ENPC1
SCHEMBL6140143 0.83 RORC (0.40) MAPTSMN1; SMN2RAPGEF3KDM4ENPC1
SCHEMBL6140783 0.81 KDM4E (0.43) MAPTSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL6140558 0.80 KDM4E (0.42) MAPTSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL6140223 0.79 RAB9A (0.41) SMN1; SMN2RAPGEF3NPC1RAB9ATDP1
SCHEMBL8323037 0.79 PSEN1 (0.42) MAPTGAAPTPN1
SCHEMBL6140092 0.78 POLB (0.41) MAPTSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL6140499 0.78 POLB (0.41) MAPTSMN1; SMN2KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6955939-B1 Memory element formation with photosensitive polymer dielectric ADVANCED MICRO DEVICES, INC. (US) 2005-10-18 US disclosed
US-6878961-B2 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. (US) 2005-04-12 US disclosed
US-20050045877-A1 PHOTOSENSITIVE POLYMERIC MEMORY ELEMENTS MORGAN STANLEY SENIOR FUNDING, INC. 2005-03-03 US disclosed
US-6825060-B1 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. 2004-11-30 US disclosed
US-6534243-B1 A coating containing a cleaving compound to trim resist features; permitting a deprotection region to form within an inner portion of the patterned resist; removing coating and deprotection region to provide a second patterned feature ADVANCED MICRO DEVICES, INC. 2003-03-18 US disclosed
US-6492075-B1 COATING WITH CLEAVING COMPOUND TO CONTROLLABLY DECREASE SIZE OF DEVELOPED RESIST ADVANCED MICRO DEVICES, INC. 2002-12-10 US disclosed
US-6274289-B1 Chemical resist thickness reduction process ADVANCED MICRO DEVICES, INC. 2001-08-14 US disclosed
US-5847218-A Sulfonium salts and chemically amplified positive resist compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-08 US disclosed