SCHEMBL6140165

SCHEMBL6140165

CC(C)(C)OC(=O)COc1ccc([S+](c2cccc(OCc3ccncc3)c2)c2cccc(OCc3ccncc3)c2)cc1.O=S(=O)([O-])c1ccccc1

nearest known ligand 0.40

Known targets — ChEMBL curated mechanism

CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.40
F2 P00734 2/20 0.40
ALDH1A1 P00352 3/20 0.39
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ADAMTS4 O75173 1/20 0.38
MMP13 P45452 1/20 0.38
POLB P06746 3/20 0.38
TSHR P16473 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
GRK2 P25098 1/20 0.38
GRK3 P35626 1/20 0.38
NPC1 O15118 1/20 0.37
GPR119 Q8TDV5 1/20 0.37
PSEN1 P49768 1/20 0.37
PSEN2 P49810 1/20 0.37
APH1B Q8WW43 1/20 0.37
NCSTN Q92542 1/20 0.37
APH1A Q96BI3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140463 0.94 F2 (0.41) PTPN1F2ALDH1A1LMNASMN1; SMN2
SCHEMBL6140576 0.94 F2 (0.41) PTPN1F2ALDH1A1LMNASMN1; SMN2
SCHEMBL6140091 0.94 PTPN1 (0.44) PTPN1F2ALDH1A1LMNASMN1; SMN2
SCHEMBL6140690 0.94 PTPN1 (0.44) PTPN1F2ALDH1A1LMNASMN1; SMN2
SCHEMBL6140200 0.88 POLB (0.42) PTPN1ALDH1A1LMNASMN1; SMN2ADAMTS4
SCHEMBL6140143 0.88 RORC (0.40) PTPN1F2ALDH1A1LMNASMN1; SMN2
SCHEMBL6140432 0.88 RORC (0.40) PTPN1F2ALDH1A1LMNASMN1; SMN2
SCHEMBL6140482 0.87 TSHR (0.44) PTPN1ALDH1A1LMNASMN1; SMN2ADAMTS4
SCHEMBL6140591 0.87 TSHR (0.44) PTPN1ALDH1A1LMNASMN1; SMN2ADAMTS4
SCHEMBL6140063 0.87 NOS3 (0.38) F2LMNAADAMTS4MMP13GRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6955939-B1 Memory element formation with photosensitive polymer dielectric ADVANCED MICRO DEVICES, INC. (US) 2005-10-18 US disclosed
US-6878961-B2 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. (US) 2005-04-12 US disclosed
US-20050045877-A1 PHOTOSENSITIVE POLYMERIC MEMORY ELEMENTS MORGAN STANLEY SENIOR FUNDING, INC. 2005-03-03 US disclosed
US-6825060-B1 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. 2004-11-30 US disclosed
US-6534243-B1 A coating containing a cleaving compound to trim resist features; permitting a deprotection region to form within an inner portion of the patterned resist; removing coating and deprotection region to provide a second patterned feature ADVANCED MICRO DEVICES, INC. 2003-03-18 US disclosed
US-6492075-B1 COATING WITH CLEAVING COMPOUND TO CONTROLLABLY DECREASE SIZE OF DEVELOPED RESIST ADVANCED MICRO DEVICES, INC. 2002-12-10 US disclosed
US-6274289-B1 Chemical resist thickness reduction process ADVANCED MICRO DEVICES, INC. 2001-08-14 US disclosed
US-5847218-A Sulfonium salts and chemically amplified positive resist compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-08 US disclosed