SCHEMBL6140643

SCHEMBL6140643

CN(C)c1ccc([S+](c2ccc(OC(C)(C)C)cc2)c2ccc(N(C)C)cc2)cc1.O=S(=O)([O-])c1ccccc1

nearest known ligand 0.37

Known targets — ChEMBL curated mechanism

CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
PGR P06401 3/20 0.36
KDM1A O60341 1/20 0.35
LMNA P02545 1/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
FFAR1 O14842 1/20 0.35
CNR2 P34972 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140116 0.90 ALDH1A1 (0.42) ALDH1A1LMNACNR2L3MBTL1MAPT
SCHEMBL6140681 0.90 ALDH1A1 (0.42) ALDH1A1LMNACNR2L3MBTL1MAPT
SCHEMBL6140043 0.89 CA12 (0.38) ALDH1A1PGRLMNASMN1; SMN2CA12
SCHEMBL2900930 0.89 PPARA (0.37) ALDH1A1LMNAMAPTSMN1; SMN2MEN1
SCHEMBL6139926 0.89 SMN1; SMN2 (0.37) ALDH1A1LMNAMAPTSMN1; SMN2MEN1
SCHEMBL6140588 0.89 SMN1; SMN2 (0.37) ALDH1A1LMNAMAPTSMN1; SMN2MEN1
SCHEMBL8318829 0.88 ALDH1A1 (0.36) ALDH1A1KDM1ALMNAKEAP1NFE2L2
SCHEMBL8324853 0.88 ALDH1A1 (0.36) ALDH1A1KDM1ALMNAKEAP1NFE2L2
SCHEMBL6140127 0.86 CA2 (0.37) ALDH1A1LMNACNR2MAPTSMN1; SMN2
SCHEMBL6140762 0.86 CA2 (0.37) ALDH1A1LMNACNR2MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6955939-B1 Memory element formation with photosensitive polymer dielectric ADVANCED MICRO DEVICES, INC. (US) 2005-10-18 US disclosed
US-6878961-B2 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. (US) 2005-04-12 US disclosed
US-20050045877-A1 PHOTOSENSITIVE POLYMERIC MEMORY ELEMENTS MORGAN STANLEY SENIOR FUNDING, INC. 2005-03-03 US disclosed
US-6825060-B1 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. 2004-11-30 US disclosed
US-6534243-B1 A coating containing a cleaving compound to trim resist features; permitting a deprotection region to form within an inner portion of the patterned resist; removing coating and deprotection region to provide a second patterned feature ADVANCED MICRO DEVICES, INC. 2003-03-18 US disclosed
US-6492075-B1 COATING WITH CLEAVING COMPOUND TO CONTROLLABLY DECREASE SIZE OF DEVELOPED RESIST ADVANCED MICRO DEVICES, INC. 2002-12-10 US disclosed
US-6274289-B1 Chemical resist thickness reduction process ADVANCED MICRO DEVICES, INC. 2001-08-14 US disclosed
US-5847218-A Sulfonium salts and chemically amplified positive resist compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-08 US disclosed