SCHEMBL6140818

SCHEMBL6140818

CC(C)(C)Oc1ccc([S+](c2ccc(OCc3ccncc3)cc2)c2ccc(OC(C)(C)C)cc2)cc1.O=S(=O)([O-])c1ccccc1

nearest known ligand 0.42

Known targets — ChEMBL curated mechanism

CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
ADAMTS4 O75173 2/20 0.41
MMP13 P45452 2/20 0.41
SMN1; SMN2 Q16637 4/20 0.40
PPARG P37231 4/20 0.40
HTT P42858 3/20 0.40
LMNA P02545 2/20 0.40
RAB9A P51151 2/20 0.40
ALDH1A1 P00352 1/20 0.40
NR2F2 P24468 1/20 0.40
AR P10275 4/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140063 0.92 NOS3 (0.38) CA12CA1CA2CA4CA5A
SCHEMBL6140238 0.91 RORC (0.44) ADAMTS4MMP13SMN1; SMN2HTTLMNA
SCHEMBL6140394 0.91 RORC (0.44) ADAMTS4MMP13SMN1; SMN2HTTLMNA
SCHEMBL6140297 0.90 LMNA (0.44) ADAMTS4MMP13SMN1; SMN2HTTLMNA
SCHEMBL6140190 0.90 LMNA (0.44) ADAMTS4MMP13SMN1; SMN2HTTLMNA
SCHEMBL6423707 0.86 F2 (0.40) SMN1; SMN2PPARGHTTNPC1F2
SCHEMBL6140690 0.86 PTPN1 (0.44) CA12CA1CA2CA4CA5A
SCHEMBL6140091 0.86 PTPN1 (0.44) CA12CA1CA2CA4CA5A
SCHEMBL6140802 0.85 NOS3 (0.41) SMN1; SMN2HTTLMNAARF2
SCHEMBL6140433 0.85 NOS3 (0.41) SMN1; SMN2HTTLMNAARF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6955939-B1 Memory element formation with photosensitive polymer dielectric ADVANCED MICRO DEVICES, INC. (US) 2005-10-18 US disclosed
US-6878961-B2 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. (US) 2005-04-12 US disclosed
US-20050045877-A1 PHOTOSENSITIVE POLYMERIC MEMORY ELEMENTS MORGAN STANLEY SENIOR FUNDING, INC. 2005-03-03 US disclosed
US-6825060-B1 Photosensitive polymeric memory elements ADVANCED MICRO DEVICES, INC. 2004-11-30 US disclosed
US-6534243-B1 A coating containing a cleaving compound to trim resist features; permitting a deprotection region to form within an inner portion of the patterned resist; removing coating and deprotection region to provide a second patterned feature ADVANCED MICRO DEVICES, INC. 2003-03-18 US disclosed
US-6492075-B1 COATING WITH CLEAVING COMPOUND TO CONTROLLABLY DECREASE SIZE OF DEVELOPED RESIST ADVANCED MICRO DEVICES, INC. 2002-12-10 US disclosed
US-6274289-B1 Chemical resist thickness reduction process ADVANCED MICRO DEVICES, INC. 2001-08-14 US disclosed
US-5847218-A Sulfonium salts and chemically amplified positive resist compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-08 US disclosed