SCHEMBL6423707

SCHEMBL6423707

CC(C)(C)Oc1ccc([S+](c2ccc(OCc3ccncc3)cc2)c2ccc(OC(C)(C)C)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.40
CYP27B1 O15528 1/20 0.40
CYP24A1 Q07973 1/20 0.40
MAPK14 Q16539 1/20 0.39
MAOB P27338 2/20 0.39
GPR119 Q8TDV5 1/20 0.39
CYP26A1 O43174 1/20 0.38
CYP3A4 P08684 1/20 0.38
PPARG P37231 4/20 0.38
KCNH2 Q12809 1/20 0.38
GRIN2B Q13224 1/20 0.38
APP P05067 1/20 0.38
MAOA P21397 1/20 0.37
NPC1 O15118 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PPARA Q07869 2/20 0.36
PPARD Q03181 1/20 0.36
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140394 0.86 RORC (0.44) MAPK14MAOBNPC1HTTSMN1; SMN2
SCHEMBL6140238 0.86 RORC (0.44) MAPK14MAOBNPC1HTTSMN1; SMN2
SCHEMBL6140818 0.86 CA12 (0.42) F2PPARGKCNH2GRIN2BNPC1
SCHEMBL6140190 0.85 LMNA (0.44) MAPK14MAOBAPPHTTSMN1; SMN2
SCHEMBL6140297 0.85 LMNA (0.44) MAPK14MAOBAPPHTTSMN1; SMN2
SCHEMBL8592230 0.83 ABCB1 (0.41) F2MAPK14PPARGKCNH2GRIN2B
SCHEMBL8937014 0.83 ABCB1 (0.41) F2MAPK14PPARGKCNH2GRIN2B
SCHEMBL6140028 0.82 RORC (0.47) CYP27B1CYP24A1MAPK14GPR119MAOA
SCHEMBL6140640 0.82 RORC (0.47) CYP27B1CYP24A1MAPK14GPR119MAOA
SCHEMBL8590702 0.81 ABCB1 (0.42) F2MAPK14PPARGKCNH2GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6955939-B1 Memory element formation with photosensitive polymer dielectric ADVANCED MICRO DEVICES, INC. (US) 2005-10-18 US disclosed