Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11983494 | 0.82 | CHRM2 (0.67) | TERTCCNA2CDK2TMEM97SIGMAR1 | |
| SCHEMBL6439791 | 0.81 | LMNA (0.43) | SIGMAR1HRH3CYP1A2MAOA | |
| SCHEMBL25570588 | 0.81 | CHRM2 (0.65) | TERTCCNA2CDK2TMEM97SIGMAR1 | |
| SCHEMBL12574650 | 0.81 | SCN8A (0.51) | TERTCCNA2CDK2TMEM97SIGMAR1 | |
| SCHEMBL27208122 | 0.81 | TDP1 (0.50) | TERTCCNA2CDK2TMEM97SIGMAR1 | |
| SCHEMBL23242442 | 0.81 | TERT (0.47) | TERTCCNA2CDK2TMEM97SIGMAR1 | |
| SCHEMBL1443953 | 0.80 | MAOA (0.64) | TERTTMEM97SIGMAR1CHRM2MEN1 | |
| SCHEMBL2478156 | 0.79 | LTA4H (0.55) | TERTCCNA2CDK2TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28446621 | 0.79 | TERT (0.43) | TERTCCNA2CDK2TMEM97SIGMAR1 | |
| SCHEMBL5915547 | 0.79 | ALDH1A1 (0.47) | TERTCCNA2CDK2TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506157-A2 | AMINO-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097575-A2 | AMINO-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |