Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MAOA | P21397 | 4/20 | 0.70 |
| ▸ | MAOB | P27338 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.70 |
| ▸ | XDH | P47989 | 1/20 | 0.70 |
| ▸ | BCL2 | P10415 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | IL2 | P60568 | 1/20 | 0.70 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6143110 | 0.89 | ALDH1A1 (0.76) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2069145 | 0.87 | RAB9A (0.80) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL571576 | 0.85 | XDH (0.84) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28648204 | 0.84 | MAPT (0.76) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6142590 | 0.83 | RAB9A (0.77) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL26145323 | 0.83 | CYP3A4 (0.74) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL738941 | 0.83 | ALDH2 (0.80) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28643838 | 0.83 | MAPT (0.74) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| Formononetin SCHEMBL15271536 | 0.83 | KDM4E (1.00) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| Isoformonentin SCHEMBL73338 | 0.83 | XDH (1.00) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951883-B2 | 2H-1-benzopyran derivatives processes for their preparation and pharmaceutical compositions thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2005-10-04 | — | — | US | disclosed |
| EP-1355906-B1 | 2H-1-BENZOPYRAN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | CHIESI FARMA SPA (IT) | 2005-01-12 | — | — | EP | disclosed |
| US-20040106595-A1 | 2H-1-benzopyran derivatives processes for their preparation and pharmaceutical compositions thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2004-06-03 | — | — | US | disclosed |
| EP-1355906-A1 | 2H-1-BENZOPYRAN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | CHIESI FARMACEUTICI S.p.A. (IT) | 2003-10-29 | — | — | EP | disclosed |
| EP-1281710-A1 | 2H-1-benzopyran derivatives, processes for their preparation and pharmaceutical compositions thereof | CHIESI FARMACEUTICI S.p.A. (IT) | 2003-02-05 | — | — | EP | disclosed |
| WO-2002059113-A1 | 2H-1-BENZOPYRAN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106595-A1 | 2H-1-benzopyran derivatives processes for their preparation and pharmaceutical compositions thereof | CYP19A1, BRCA1, HPD | MAPT 2499/4885ALDH1A1 793/4885SMN1; SMN2 2778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.