Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712255 | 0.91 | HSD17B10 (0.71) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL23276221 | 0.85 | HSD17B10 (0.63) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL29444214 | 0.83 | HSD17B10 (0.61) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL14690428 | 0.83 | HSD17B10 (0.61) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL4387913 | 0.82 | HSD17B10 (0.76) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL10492954 | 0.81 | PRSS1 (0.48) | ALDH1A1KMT2A | |
| SCHEMBL5087773 | 0.80 | HSD17B10 (0.57) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL14689568 | 0.80 | HSD17B10 (0.57) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL29444234 | 0.80 | HSD17B10 (0.57) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL789770 | 0.80 | KMT2A (0.41) | HSD17B10HPGDALOX15MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496064-A1 | Nitrate active principle | Nicox S.A (FR) | 2005-01-12 | — | — | EP | disclosed |
| EP-1347744-B1 | SOLID DISPERSIONS OF NITRATE ACTIVE PRINCIPLES | NICOX SA (FR) | 2004-09-08 | — | — | EP | disclosed |
| US-20040071777-A1 | Solid dispersions of nitrate active principles | NICOX S.A. (FR) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040071777-A1 | Solid dispersions of nitrate active principles | PGD, NOS3, SORD | HSD17B10 1164/4885HPGD 24/4885ALOX15 1194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.