Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151485 | 0.82 | MAPT (0.50) | LMNAKMT2ADRD3MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL6413349 | 0.81 | MAPT (0.49) | HTR1ALMNAKMT2ADRD2DRD4 | |
| SCHEMBL6945690 | 0.79 | SIRT6 (0.65) | SIRT6HTR1ALMNAKMT2APOLB | |
| SCHEMBL5209234 | 0.77 | MAPT (0.67) | SIRT6HTR1ALMNAKMT2APOLB | |
| SCHEMBL6151173 | 0.77 | GAA (0.55) | HTR1AKMT2ADRD2MAPTMAPK1 | |
| SCHEMBL2730000 | 0.76 | KDM4E (0.63) | SIRT6HTR1ALMNAKMT2APOLB | |
| SCHEMBL28781525 | 0.76 | SIRT6 (0.57) | SIRT6HTR1ALMNAKMT2APOLB | |
| Hydrochloric Acid SCHEMBL6410951 | 0.76 | GAA (0.54) | HTR1AKMT2ADRD2MAPTMAPK1 | |
| SCHEMBL5743368 | 0.76 | HTR1A (0.61) | SIRT6HTR1ALMNAKMT2APOLB | |
| SCHEMBL5187796 | 0.76 | SIRT6 (0.60) | SIRT6HTR1ALMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050120494-A1 | Triazacyclononane derivatives substituted on at least one of the nitrogen atoms with a substituted or unsubstituted 4'-aminophenyl group, for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-06-09 | — | — | US | disclosed |
| EP-1518860-A1 | Triazacyclononane derivatives substituted on at least one of the nitrogene atoms by a 4-aminophenyle group for dyeing keratinic fibres | L'OREAL (FR) | 2005-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050120494-A1 | Triazacyclononane derivatives substituted on at least one of the nitrogen atoms with a substituted or unsubstituted 4'-aminophenyl group, for dyeing keratin fibres | KRT18, TUBB6, TUBB1 | SIRT6 1570/4885HTR1A 3011/4885LMNA 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.