Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151258 | 0.88 | USP2 (0.46) | USP2TP53KMT2AMEN1CES2 | |
| SCHEMBL3282912 | 0.82 | NPC1 (0.63) | USP2TP53KMT2AMEN1HPGD | |
| SCHEMBL29861033 | 0.82 | NPC1 (0.63) | USP2TP53KMT2AMEN1HPGD | |
| SCHEMBL7129795 | 0.80 | MEN1 (0.62) | USP2TP53KMT2AMEN1CES2 | |
| SCHEMBL6150785 | 0.79 | TP53 (0.45) | USP2TP53KMT2AMEN1CES2 | |
| SCHEMBL6150783 | 0.79 | TP53 (0.45) | USP2TP53KMT2AMEN1CES2 | |
| SCHEMBL14356156 | 0.77 | TP53 (0.47) | USP2TP53KMT2AMEN1CES2 | |
| SCHEMBL766761 | 0.77 | KDM4E (0.70) | USP2KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL5710874 | 0.76 | ALDH1A1 (0.65) | KMT2AMEN1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL17263411 | 0.76 | KDM4E (0.54) | USP2TP53KMT2AMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427770-B1 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GEN ELECTRIC (US) | 2005-01-19 | — | — | EP | claimed |
| EP-1427770-A1 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2004-06-16 | — | — | EP | claimed |
| US-20030120025-A1 | Process for the production of polycarbonate | GENERAL ELECTRIC COMPANY | 2003-06-26 | — | — | US | claimed |
| WO-2003022905-A1 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2003-03-20 | — | — | WO | claimed |
| US-6525163-B1 | Reducing static charge, improving heat aging, and lowering water absorption by increasing endcap levels | GENERAL ELECTRIC COMPANY | 2003-02-25 | — | — | US | claimed |
| EP-1427770-B1 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GEN ELECTRIC (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-1427770-A1 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| US-20030120025-A1 | Process for the production of polycarbonate | GENERAL ELECTRIC COMPANY | 2003-06-26 | — | — | US | disclosed |
| WO-2003022905-A1 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2003-03-20 | — | — | WO | disclosed |
| US-6525163-B1 | Reducing static charge, improving heat aging, and lowering water absorption by increasing endcap levels | GENERAL ELECTRIC COMPANY | 2003-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030120025-A1 | Process for the production of polycarbonate | RNGTT, CAPG, RPL30 | USP2 1281/4885TP53 1401/4885KMT2A 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.