Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 10/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.49 |
| ▸ | HTR3B | O95264 | 5/20 | 0.49 |
| ▸ | HTR3A | P46098 | 5/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.49 |
| ▸ | HTR5A | P47898 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 3/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419500 | 0.98 | ADRB1 (0.71) | ADRB1GAARAD52MAPTRECQL | |
| SCHEMBL6151312 | 0.97 | ADRB1 (0.69) | ADRB1GAARAD52MAPTRECQL | |
| SCHEMBL5206787 | 0.92 | ADRB1 (0.63) | ADRB1GAARAD52MAPTRECQL | |
| SCHEMBL15358759 | 0.85 | GAA (0.77) | ADRB1GAARAD52MAPTRECQL | |
| SCHEMBL6151434 | 0.85 | GAA (0.77) | ADRB1GAARAD52MAPTRECQL | |
| SCHEMBL21760107 | 0.84 | ADRB1 (0.71) | ADRB1GAARAD52MAPTRECQL | |
| SCHEMBL8071214 | 0.82 | MAPT (0.61) | ADRB1MAPTRECQLHTR7HTR3E | |
| SCHEMBL2923577 | 0.82 | GAA (0.67) | ADRB1GAARAD52MAPTRECQL | |
| SCHEMBL7032717 | 0.82 | GAA (0.67) | ADRB1GAARAD52MAPTRECQL | |
| SCHEMBL221254 | 0.82 | ADRB1 (1.00) | ADRB1HTR7HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050120494-A1 | Triazacyclononane derivatives substituted on at least one of the nitrogen atoms with a substituted or unsubstituted 4'-aminophenyl group, for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-06-09 | — | — | US | claimed |
| EP-1518860-A1 | Triazacyclononane derivatives substituted on at least one of the nitrogene atoms by a 4-aminophenyle group for dyeing keratinic fibres | L'OREAL (FR) | 2005-03-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050120494-A1 | Triazacyclononane derivatives substituted on at least one of the nitrogen atoms with a substituted or unsubstituted 4'-aminophenyl group, for dyeing keratin fibres | KRT18, TUBB6, TUBB1 | ADRB1 3709/4885GAA 4694/4885RAD52 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.