Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127145 | 0.83 | MAOB (0.50) | ALDH1A1NPC1SMN1; SMN2CA12CA1 | |
| SCHEMBL17041364 | 0.80 | MAOB (0.56) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL20873387 | 0.78 | MTNR1B (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2CA1 | |
| SCHEMBL5178079 | 0.77 | CA12 (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2CA12 | |
| SCHEMBL418525 | 0.76 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9ASMN1; SMN2CA12 | |
| SCHEMBL10578987 | 0.76 | HTT (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2CA12 | |
| SCHEMBL10346038 | 0.74 | RAB9A (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2CA12 | |
| SCHEMBL28344902 | 0.74 | CA1 (0.52) | ALDH1A1NPC1RAB9ACA12CA1 | |
| SCHEMBL1323789 | 0.74 | APP (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2CA12 | |
| 1,4-Dimethoxybenzene SCHEMBL27368038 | 0.73 | CA1 (0.58) | ALDH1A1NPC1RAB9ASMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563056-B | Triazoles for modulating intracellular calcium homeostasis | 巴斯克大学 | 2022-08-16 | — | — | CN | disclosed |
| US-11377427-B2 | Triazoles for regulating intracellular calcium homeostasis | UNIVERSIDAD DEL PAIS VASCO (ES) | 2022-07-05 | — | — | US | disclosed |
| EP-3466933-B1 | TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS | UNIV DEL PAIS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (ES) | 2020-12-02 | — | — | EP | disclosed |
| US-20200317625-A1 | TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS | UNIVERSIDAD DEL PAIS VASCO (ES) | 2020-10-08 | — | — | US | disclosed |
| EP-3466933-A1 | TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS | Universidad del Pais Vasco (ES) | 2019-04-10 | — | — | EP | disclosed |
| EP-1334095-B1 | PROCESS FOR THE PREPARATION OF PGD2 ANTAGONIST | SHIONOGI & CO (JP) | 2005-01-19 | — | — | EP | disclosed |
| EP-1334095-A4 | PROCESS FOR THE PREPARATION OF PGD2 ANTAGONIST | SHIONOGI & CO (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6693203-B2 | REACTING NOPINONE ENOLATE WITH ALKYL 7-HALO-5-HEPTYNOATE, REACTING PRODUCT WITH HYDROXYLAMINE, TREATING WITH TITANIUM TRICHLORIDE AND BORANE REAGENT, HYDROGENATING, REACTING WITH 5-HYDROXY-4-BENZOTHIOPHENECARBOXYLIC ACID, HYDROLYZING | SHIONOGI & CO., LTD (JP) | 2004-02-17 | — | — | US | disclosed |
| US-20030199702-A1 | Process for the preparation of pgd2 antagonist | LARSEN ROBERT (US) | 2003-10-23 | — | — | US | disclosed |
| EP-1334095-A1 | PROCESS FOR THE PREPARATION OF PGD2 ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032892-A1 | PROCESS FOR THE PREPARATION OF PGD2 ANTAGONIST | SHIONOGI & CO., LTD (JP) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377427-B2 | Triazoles for regulating intracellular calcium homeostasis | RYR1, ATP2A3, RYR2 | ALDH1A1 3347/4885NPC1 2220/4885RAB9A 1224/4885 |
| US-20200317625-A1 | TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS | RYR1, ATP2A3, RYR2 | ALDH1A1 3347/4885NPC1 2220/4885RAB9A 1224/4885 |
| US-20030199702-A1 | Process for the preparation of pgd2 antagonist | PTGDR, PTGDR2, PTGER2 | ALDH1A1 3338/4885NPC1 4429/4885RAB9A 4615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.