Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887218 | 0.83 | PKM (0.46) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5081752 | 0.82 | PKM (0.34) | PKML3MBTL1ALDH1A1 | |
| SCHEMBL164232 | 0.81 | L3MBTL1 (0.58) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL14493665 | 0.81 | L3MBTL1 (0.58) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13589980 | 0.81 | L3MBTL1 (0.58) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1061966 | 0.79 | L3MBTL1 (0.61) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5486305 | 0.79 | L3MBTL1 (0.56) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4712251 | 0.79 | L3MBTL1 (0.61) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4712253 | 0.79 | L3MBTL1 (0.61) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL692515 | 0.79 | LMNA (0.30) | PKMSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948361-B1 | MAGNETIC RESONANCE BLOOD POOL AGENTS | MALLINCKRODT INC (US) | 2005-01-26 | — | — | EP | claimed |
| EP-0948361-A4 | MAGNETIC RESONANCE BLOOD POOL AGENTS | MALLINCKRODT MEDICAL INC (US) | 2001-02-07 | — | — | EP | claimed |
| EP-0948361-A1 | MAGNETIC RESONANCE BLOOD POOL AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1999-10-13 | — | — | EP | claimed |
| US-5961953-A | CONTAINING BICYCLO(2.2.2)OCTANE, ADAMANTANE, OR DICYCLOHEXYLACETYL GROUPS AND CHELATING GROUPS | MALLINCKRODT INC. (US) | 1999-10-05 | — | — | US | claimed |
| US-5888476-A | ADMINISTERING A GADOLINIUM COMPLEX AS A CONTRAST AGENT FOR MAGNETIC RESONANCE IMAGING WHICH INCREASE RELAXIVITY OF WATER PROTONS SURROUNDING THE TISSUE | MALLINCKRODT MEDICAL, INC. (US) | 1999-03-30 | — | — | US | claimed |
| WO-1998020908-A1 | MAGNETIC RESONANCE BLOOD POOL AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1998-05-22 | — | — | WO | claimed |