SCHEMBL692515

SCHEMBL692515

O=[C]C12CC3CC(C1)CC([C]=O)(C3)C2

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11089627 0.84 THRB (0.42)
SCHEMBL11088099 0.84 DPP4 (0.32)
SCHEMBL11091802 0.84 PKM (0.47) PKM
SCHEMBL465574 0.82 GRIN2D (0.38) LMNASMN1; SMN2
SCHEMBL6152600 0.79 PKM (0.47) LMNASMN1; SMN2PKM
SCHEMBL11090307 0.79
SCHEMBL7517207 0.76
SCHEMBL11259057 0.73 GRIN2D (0.58) LMNA
SCHEMBL14641099 0.72 PGR (0.32) PKM
SCHEMBL2323149 0.72 PKM (0.30) PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107400236-A Polyamic acid composition, its polyamidoimide film and the method for preparing polyamidoimide film SK新技术株式会社 2017-11-28 CN disclosed
EP-2421904-B1 PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD GRACE W R & CO (US) 2015-06-24 EP disclosed
US-8288304-B2 Procatalyst composition with adamantane and method DOW GLOBAL TECHNOLOGIES LLC (US) 2012-10-16 US disclosed
EP-2421904-A1 PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD Dow Global Technologies LLC (US) 2012-02-29 EP disclosed
WO-2010123775-A1 PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-28 WO disclosed
US-20100273966-A1 Procatalyst Composition with Adamantane and Method W. R. GRACE & CO.-CONN. 2010-10-28 US disclosed