Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12104275 | 0.90 | PKM (0.42) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6152600 | 0.83 | PKM (0.47) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL4098563 | 0.80 | ALDH1A1 (0.35) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL14493665 | 0.80 | L3MBTL1 (0.58) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL164232 | 0.80 | L3MBTL1 (0.58) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13589980 | 0.80 | L3MBTL1 (0.58) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL3871913 | 0.79 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL3869634 | 0.79 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL4712251 | 0.78 | L3MBTL1 (0.61) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4712253 | 0.78 | L3MBTL1 (0.61) | PKML3MBTL1ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275112-A1 | Invention Concerning Aminoadamantane Compounds | SCHREINER PETER R | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275112-A1 | Invention Concerning Aminoadamantane Compounds | GABRA5, GABRA1, GABRA4 | PKM 2313/4885L3MBTL1 4233/4885ALDH1A1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.