Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6152624 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7733742 | 0.70 | GSK3A (0.33) | — | |
| Hydrochloric Acid SCHEMBL4525487 | 0.68 | ABCG2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL5486777 | 0.68 | ABCG2 (0.51) | — | |
| Toluene SCHEMBL7669664 | 0.62 | LMNA (0.44) | — | |
| Hydrochloric Acid SCHEMBL5695988 | 0.61 | CASP3 (0.32) | — | |
| Hydrochloric Acid SCHEMBL3270111 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL5138208 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL646564 | 0.57 | PNMT (0.39) | — | |
| Hydrochloric Acid SCHEMBL3672120 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1543045-A1 | OLEFIN POLYMERIZATION PROCESS | Equistar Chemicals, LP (US) | 2005-06-22 | — | — | EP | disclosed |
| US-6765074-B2 | SUPPORTED INDENOINDOLYL CATALYST SYSTEM AND AN ORGANOBORON OR ORGANOALUMINUM-TREATED SOLID | EQUISTAR CHEMICALS, LP | 2004-07-20 | — | — | US | disclosed |
| EP-1412399-A1 | SUPPORTED OLEFIN POLYMERIZATION CATALYSTS | Equistar Chemicals, LP (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2004029102-A1 | OLEFIN POLYMERIZATION PROCESS | EQUISTAR CHEMICALS, LP (US) | 2004-04-08 | — | — | WO | disclosed |
| US-20040063876-A1 | Olefin polymerization process | EQUISTAR CHEMICALS, LP | 2004-04-01 | — | — | US | disclosed |
| US-6583242-B2 | Alumoxane, organometallic complex containing an indenoindolyl ligand, an activator; copolymerizing ethylene with a C3-C10 alpha-olefin | EQUISTAR CHEMICALS, LP | 2003-06-24 | — | — | US | disclosed |
| US-20030050413-A1 | Supported olefin polymerization catalysts | EQUISTAR CHEMICALS, LP | 2003-03-13 | — | — | US | disclosed |
| WO-2003011921-A1 | SUPPORTED OLEFIN POLYMERIZATION CATALYSTS | EQUISTAR CHEMICALS, LP (US) | 2003-02-13 | — | — | WO | disclosed |