Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615179 | 0.79 | POLB (0.32) | PRKDCERN1 | |
| SCHEMBL613905 | 0.79 | ERN1 (0.31) | PRKDCERN1 | |
| SCHEMBL616113 | 0.78 | MCL1 (0.31) | ERN1 | |
| SCHEMBL614736 | 0.78 | PRKDC (0.40) | PRKDCERN1 | |
| SCHEMBL2579726 | 0.78 | NFE2L2 (0.31) | ERN1 | |
| SCHEMBL10734331 | 0.69 | ALDH1A1 (0.36) | PRKDCERN1 | |
| SCHEMBL5096718 | 0.65 | ALDH1A1 (0.38) | PRKDCERN1 | |
| SCHEMBL26353994 | 0.65 | ERN1 (0.47) | PRKDCERN1 | |
| SCHEMBL2674287 | 0.64 | CYP1A2 (0.44) | ERN1 | |
| SCHEMBL21224376 | 0.62 | PRKDC (0.49) | PRKDCERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466287-B2 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-20120041204-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2012-02-16 | — | — | US | disclosed |
| US-8067595-B2 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20090023927-A1 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1900740-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | Kabushiki Kaisha Yakult Honsha (JP) | 2008-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041204-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | TKT, DCK, COASY | PRKDC 123/4885ERN1 1153/4885 |
| US-20090023927-A1 | Process for producing tricyclic ketone | TKT, DCK, COASY | PRKDC 123/4885ERN1 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.