Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613905 | 0.83 | ERN1 (0.31) | ERN1PRKDC | |
| SCHEMBL2674287 | 0.82 | CYP1A2 (0.44) | POLBCYP1A2CYP2C9CYP2C19ERN1 | |
| SCHEMBL614736 | 0.81 | PRKDC (0.40) | ERN1PRKDC | |
| SCHEMBL616113 | 0.81 | MCL1 (0.31) | ERN1 | |
| SCHEMBL2579726 | 0.81 | NFE2L2 (0.31) | ERN1 | |
| SCHEMBL615268 | 0.79 | PRKDC (0.31) | ERN1PRKDC | |
| SCHEMBL5372841 | 0.79 | POLB (0.51) | POLBCYP1A2CYP2C9CYP2C19ERN1 | |
| SCHEMBL25272811 | 0.77 | ALDH1A1 (0.36) | POLBCYP1A2CYP2C9CYP2C19ERN1 | |
| SCHEMBL6342720 | 0.69 | PKM (0.34) | ERN1 | |
| SCHEMBL5096718 | 0.68 | ALDH1A1 (0.38) | CYP1A2CYP2C9CYP2C19ERN1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466287-B2 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-20120041204-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2012-02-16 | — | — | US | disclosed |
| US-8067595-B2 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20090023927-A1 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1900740-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | Kabushiki Kaisha Yakult Honsha (JP) | 2008-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041204-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | TKT, DCK, COASY | POLB 691/4885CYP1A2 110/4885CYP2C9 89/4885 |
| US-20090023927-A1 | Process for producing tricyclic ketone | TKT, DCK, COASY | POLB 691/4885CYP1A2 110/4885CYP2C9 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.