Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.46 |
| ▸ | UBE2M | P61081 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153691 | 0.87 | MCHR1 (0.60) | ACHEBACE1MCHR1SIGMAR1 | |
| SCHEMBL6154946 | 0.85 | LTA4H (0.52) | LTA4HACHEJAK2JAK1TYK2 | |
| SCHEMBL6154103 | 0.84 | MCHR1 (0.51) | LTA4HBCHEACHEBACE1JAK2 | |
| SCHEMBL6154970 | 0.83 | MCHR1 (0.56) | ACHEBACE1MCHR1SIGMAR1ROCK2 | |
| SCHEMBL6155471 | 0.83 | LTA4H (0.50) | LTA4HACHEBACE1JAK2JAK1 | |
| SCHEMBL6153444 | 0.83 | SIGMAR1 (0.55) | LTA4HJAK2JAK1TYK2JAK3 | |
| Hydrochloric Acid SCHEMBL6154430 | 0.83 | SIGMAR1 (0.54) | LTA4HJAK2JAK1TYK2JAK3 | |
| SCHEMBL6154543 | 0.82 | SLC6A12 (0.59) | LTA4HACHEJAK2JAK1TYK2 | |
| SCHEMBL6155299 | 0.82 | JAK2 (0.53) | LTA4HJAK2JAK1TYK2JAK3 | |
| SCHEMBL6153708 | 0.81 | JAK2 (0.52) | LTA4HJAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | LTA4H 1043/4885BCHE 923/4885ACHE 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.