Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PI4KA | P42356 | 2/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.35 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479715 | 0.74 | DPP4 (0.50) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2115830 | 0.74 | PI4KA (0.55) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2696766 | 0.74 | ALDH1A1 (0.41) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2008437 | 0.71 | LMNA (0.57) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL545835 | 0.67 | PDPK1 (0.41) | ALDH1A1LRRK2XDHPDPK1GDA | |
| SCHEMBL2877709 | 0.67 | XDH (0.56) | XDHPDPK1GDACDK2DPP4 | |
| SCHEMBL2867588 | 0.67 | PDPK1 (0.66) | PDPK1GDACDK2DPP4MAP3K5 | |
| Adenine SCHEMBL5548908 | 0.62 | ALDH1A1 (0.54) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2473003 | 0.61 | ALDH1A1 (0.64) | ALDH1A1XDHLMNAPDPK1GDA | |
| Hypoxanthine SCHEMBL25381 | 0.59 | ALDH1A1 (1.00) | ALDH1A1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499627-A2 | NUCLEASE RESISTANT CHIMERIC OLIGONUCLEOTIDES | ISIS Pharmaceuticals, Inc. (US) | 2005-01-26 | — | — | EP | claimed |
| WO-2003004602-A2 | NUCLEASE RESISTANT CHIMERIC OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2003-01-16 | — | — | WO | claimed |
| US-5599582-A | Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1997-02-04 | — | — | US | claimed |
| US-5569739-A | Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1996-10-29 | — | — | US | claimed |
| US-5326643-A | Adhesive layer in multi-level packaging and organic material as a metal diffusion barrier | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1994-07-05 | — | — | US | claimed |
| EP-0536606-A2 | An adhesive layer in multilevel packaging and organic material as a metal diffusion barrier | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1993-04-14 | — | — | EP | claimed |