Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883362 | 0.85 | KMT2A (0.45) | ALDH1A1TSHRKMT2ALMNAMEN1 | |
| SCHEMBL27513255 | 0.84 | TSHR (0.45) | ALDH1A1TSHRKMT2ALMNAMEN1 | |
| SCHEMBL9773219 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNAHPGD | |
| SCHEMBL16622585 | 0.77 | CTSK (0.43) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL16622604 | 0.76 | KMT2A (0.36) | ALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL28081042 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRGPR88HPGD | |
| SCHEMBL28081040 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRGPR88HPGD | |
| SCHEMBL9681180 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRKMT2AHPGDPOLB | |
| SCHEMBL6270165 | 0.72 | LMNA (0.46) | ALDH1A1TSHRKMT2ALMNAMEN1 | |
| SCHEMBL16622551 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KMT2AGPR88LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1078919-B1 | SYNTHESIS OF ALPHA-AMINO-ALPHA',ALPHA'-DIHALOKETONES AND PROCESS FOR THE PREPARATION OF BETA)-AMINO ACID DERIVATIVES BY THE USE OF THE SAME | KANEKA CORP (JP) | 2005-12-07 | — | — | EP | disclosed |