SCHEMBL615494

SCHEMBL615494

CCCCCCCCCCCCCCC(C(=O)OCCCCCCCCCC)C(C)CCCC

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.47
RAD52 P43351 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
EPHX1 P07099 1/20 0.44
TSHR P16473 3/20 0.43
ZDHHC7 Q9NXF8 1/20 0.42
MAPT P10636 1/20 0.42
HCAR2 Q8TDS4 1/20 0.41
FAAH O00519 2/20 0.41
CA2 P00918 1/20 0.41
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
PLA2G2C Q5R387 1/20 0.40
SMPD1 P17405 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5918687 1.00 NAAA (0.47) NAAARAD52NPSR1EPHX1TSHR
SCHEMBL2984689 1.00 NAAA (0.47) NAAARAD52NPSR1EPHX1TSHR
SCHEMBL611992 1.00 NAAA (0.47) NAAARAD52NPSR1EPHX1TSHR
SCHEMBL2961846 1.00 NAAA (0.47) NAAARAD52NPSR1EPHX1TSHR
SCHEMBL5315110 1.00 NAAA (0.47) NAAARAD52NPSR1EPHX1TSHR
SCHEMBL157764 1.00 NAAA (0.47) NAAARAD52NPSR1EPHX1TSHR
SCHEMBL2980882 0.98 NAAA (0.48) NAAARAD52NPSR1EPHX1TSHR
SCHEMBL19025364 0.98 NAAA (0.48) NAAARAD52NPSR1EPHX1TSHR
SCHEMBL17433676 0.98 NAAA (0.48) NAAARAD52NPSR1EPHX1TSHR
SCHEMBL730515 0.98 NAAA (0.48) NAAARAD52NPSR1EPHX1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101155571-B Stick solid cosmetic and process for producing the same SHISEDO CO LTD 2012-07-18 CN claimed
CN-118338884-A Oxidizing agent and acid based systems and therapies for enhancing skin appearance 欧莱雅 2024-07-12 CN disclosed
CN-118255914-A Copolymer having carbosiloxane dendrimer structure, and composition, cosmetic raw material, film-forming agent and cosmetic containing the copolymer 陶氏东丽株式会社 2024-06-28 CN disclosed
CN-114641274-B Oil-in-water type composition 株式会社资生堂 2024-06-04 CN disclosed
CN-117942282-A Cosmetic composition JNTL消费者健康株式会社 2024-04-30 CN disclosed
CN-117897131-A Method for producing film 花王株式会社 2024-04-16 CN disclosed
CN-114040746-B Oil-in-water type cleansing cosmetic 陶氏东丽株式会社 2024-02-27 CN disclosed
CN-113710226-B Cosmetic material 陶氏东丽株式会社 2024-02-27 CN disclosed
CN-113226254-B Oil-in-water emulsion cosmetic containing retinol 株式会社资生堂 2024-02-23 CN disclosed
CN-109153790-B Organosilicon particles, cosmetics, paint and resin containing same 陶氏东丽株式会社 2024-02-20 CN disclosed
EP-1595936-A1 ANTIOXIDATIVE COMPOSITION AND COMPOSITION FOR EXTERNAL USE MITSUBISHI CORPORATION (JP) 2005-11-16 EP disclosed
EP-1557159-A1 SKIN PREPARATIONS FOR EXTERNAL USE SHISEIDO COMPANY LIMITED (JP) 2005-07-27 EP disclosed
US-20040197361-A1 External preparation for the skin SHISEIDO COMPANY, LTD. (JP) 2004-10-07 US disclosed
US-6784271-B2 ADDITION REACTION BETWEEN A HYDROGEN SILOXANE AND A COMPOUND WITH A TERMINAL DOUBLE BOND IN THE PRESENCE OF A PLATINUM CATALYST SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-08-31 US disclosed
EP-1430905-A1 EXTERNAL PREPARATION FOR THE SKIN SHISEIDO COMPANY LIMITED (JP) 2004-06-23 EP disclosed
CN-1120745-C Microcapsule containing core material and its producing method NARIWAKASEI CO LTD (JP) 2003-09-10 CN disclosed
US-20030158363-A1 Odorless modified silicone compound,cosmetic preparation containing the same, and method of purifying modified silicone compound having branch polymer comprising hydrophilic group SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-08-21 US disclosed
US-6607736-B2 Endermic liniment comprising diethoxy ethyl succinate and humectant SHISEIDO COMPANY, LTD. (JP) 2003-08-19 US disclosed
US-20030091603-A1 Skin preparations for external use SHISEIDO COMPANY, LTD. (JP) 2003-05-15 US disclosed
EP-1153602-A1 SKIN PREPARATIONS FOR EXTERNAL USE SHISEIDO COMPANY LIMITED (JP) 2001-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030091603-A1 Skin preparations for external use CUTA, POLR1C, ACMSD NAAA 1925/4885RAD52 37/4885NPSR1 1648/4885
US-20040197361-A1 External preparation for the skin CUTA, DDOST, DSG1 NAAA 1014/4885RAD52 226/4885NPSR1 935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.