Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033772 | 0.86 | AGTR1 (0.41) | POLBSMN1; SMN2GRM5XDHAGTR1 | |
| SCHEMBL6188044 | 0.86 | GRM5 (0.39) | POLBSMN1; SMN2GRM5XDHKCNN4 | |
| SCHEMBL7352872 | 0.82 | ABCG2 (0.41) | POLBSMN1; SMN2XDHAGTR1ABCG2 | |
| SCHEMBL4888374 | 0.80 | POLB (0.39) | POLBSMN1; SMN2ABCG2NPC1RAB9A | |
| SCHEMBL3393694 | 0.79 | RAB9A (0.47) | POLBSMN1; SMN2ABCG2NPC1RAB9A | |
| SCHEMBL7348668 | 0.79 | POLB (0.40) | POLBSMN1; SMN2GRM5XDHAGTR1 | |
| SCHEMBL6156586 | 0.78 | POLB (0.47) | POLBSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL7346198 | 0.77 | NPSR1 (0.50) | POLBSMN1; SMN2GRM5KCNN4ABCG2 | |
| SCHEMBL4617609 | 0.76 | SMN1; SMN2 (0.56) | POLBSMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL7772778 | 0.76 | ABCG2 (0.44) | POLBSMN1; SMN2AGTR1ABCG2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849911-A | Antivirally active heterocyclic azahexane derivatives | NOVARTIS FINANCE CORPORATION (US) | 1998-12-15 | — | — | US | disclosed |