Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | METAP2 | P50579 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397635 | 0.87 | SLC6A3 (0.44) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL8827881 | 0.85 | LMNA (0.39) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL44290 | 0.84 | LMNA (0.35) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL8844752 | 0.83 | MAPT (0.33) | LMNAMETAP2METAP1HDAC6MAPT | |
| SCHEMBL44289 | 0.83 | MAPT (0.33) | LMNAMETAP2METAP1HDAC6MAPT | |
| SCHEMBL27464332 | 0.82 | ATM (0.34) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL11253188 | 0.82 | HSD17B10 (0.52) | LMNAMETAP2METAP1HDAC6KMT2A | |
| SCHEMBL7707716 | 0.80 | SLC22A6 (0.44) | LMNAKMT2AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL14690221 | 0.80 | MAPT (0.32) | LMNAMETAP2METAP1HDAC6MAPT | |
| SCHEMBL2534586 | 0.80 | MEN1 (0.38) | LMNAMETAP2METAP1HDAC6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434582-A | Phenyl (benzotriazolyl) benzoate compound | UNIV EAST CHINA SCIENCE & TECH (CN) | 2009-05-20 | — | — | CN | disclosed |
| EP-1499743-A1 | MEANS AND METHODS FOR DETECTING ENDOGLYCOSIDASE ACTIVITY | ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM (NL) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003093497-A1 | MEANS AND METHODS FOR DETECTING ENDOGLYCOSIDASE ACTIVITY | ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM (NL) | 2003-11-13 | — | — | WO | disclosed |