Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155017 | 0.87 | LMNA (0.54) | SLC6A3LMNAPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL8827881 | 0.84 | LMNA (0.39) | LMNAPOLBALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7707716 | 0.80 | SLC22A6 (0.44) | LMNAPOLBRAB9AALDH1A1HPGD | |
| SCHEMBL8844752 | 0.79 | MAPT (0.33) | LMNAPOLBMAPTKDM4EMETAP2 | |
| SCHEMBL44289 | 0.79 | MAPT (0.33) | LMNAPOLBHPGDMAPTKDM4E | |
| SCHEMBL7403840 | 0.79 | GAA (0.47) | LMNAPOLBALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL44290 | 0.78 | LMNA (0.35) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL14690221 | 0.77 | MAPT (0.32) | LMNAPOLBMAPTKDM4EMETAP2 | |
| SCHEMBL717583 | 0.77 | PKN1 (0.50) | LMNAPOLBALDH1A1KMT2AMAPT | |
| SCHEMBL2534586 | 0.77 | MEN1 (0.38) | LMNAPOLBKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255748-A1 | BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001060813-A1 | BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |