SCHEMBL6156510

SCHEMBL6156510

CON=C(C(=O)OC)c1ccccc1C(ON)=C(C)C1CC1c1c(Cl)cccc1Cl

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.38
SLC6A3 Q01959 1/20 0.31
SLC9A1 P19634 1/20 0.31
ALDH1A1 P00352 1/20 0.31
FABP7 O15540 1/20 0.31
FABP5 Q01469 1/20 0.31
HPGD P15428 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156363 0.91 SLC9A1 (0.34) SLC9A1ALDH1A1FABP7FABP5HPGD
SCHEMBL6157642 0.90 SLC6A3 (0.30) SLC6A3SLC9A1
SCHEMBL7700157 0.77 HIF1A (0.48) HIF1AALDH1A1
SCHEMBL6156508 0.77 HIF1A (0.48) HIF1AALDH1A1
SCHEMBL6158168 0.77 HIF1A (0.48) HIF1AALDH1A1
SCHEMBL6156945 0.77 HIF1A (0.48) HIF1AALDH1A1
SCHEMBL6155978 0.77 HIF1A (0.48) HIF1AALDH1A1
SCHEMBL7036504 0.76 HIF1A (0.38) HIF1AHPGDRAB9ASMN1; SMN2L3MBTL1
SCHEMBL6155140 0.73 HIF1A (0.40) HIF1ASLC6A3ALDH1A1HPGDRAB9A
SCHEMBL6155148 0.73 HIF1A (0.40) HIF1ASLC6A3ALDH1A1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1286955-B1 ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2005-02-02 EP disclosed