Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.30 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158814 | 0.82 | PRKDC (0.37) | PDE3BPDE3AKDM4EALDH1A1PRKDC | |
| SCHEMBL6156255 | 0.81 | MEN1 (0.38) | RAB9APDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL8371288 | 0.81 | PDE3B (0.39) | PDE3BPDE3AALDH1A1HSD17B10PRKDC | |
| SCHEMBL6156060 | 0.80 | PDE3B (0.37) | PDE3BPDE3AALDH1A1PRKDC | |
| SCHEMBL6165736 | 0.79 | PTPN1 (0.38) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL6156254 | 0.79 | KDM4E (0.35) | RAB9AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL6155845 | 0.79 | KMT2A (0.34) | RAB9AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7784158 | 0.76 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL7784152 | 0.71 | LMNA (0.35) | KDM4E | |
| SCHEMBL7608589 | 0.71 | LMNA (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894805-B1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2005-02-09 | — | — | EP | disclosed |
| EP-0894805-A1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 1999-02-03 | — | — | EP | disclosed |