Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156254 | 0.85 | KDM4E (0.35) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL7784158 | 0.81 | ALDH1A1 (0.45) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL6156255 | 0.81 | MEN1 (0.38) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL6158814 | 0.80 | PRKDC (0.37) | KDM4EALDH1A1 | |
| SCHEMBL6155515 | 0.79 | RAB9A (0.33) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8371288 | 0.79 | PDE3B (0.39) | ALDH1A1HSD17B10NPSR1 | |
| SCHEMBL6156060 | 0.78 | PDE3B (0.37) | ALDH1A1LMNA | |
| SCHEMBL7608589 | 0.77 | LMNA (0.36) | KDM4ELMNACA12CA9HSP90AA1 | |
| SCHEMBL7784152 | 0.77 | LMNA (0.35) | KDM4ELMNAHSP90AA1HSP90AB1 | |
| SCHEMBL6165736 | 0.77 | PTPN1 (0.38) | KDM4EALDH1A1HSD17B10HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894805-B1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2005-02-09 | — | — | EP | disclosed |
| US-5968939-A | ANTIBIOTICS FROM AMINOOXOBENZOPYRAN COMPOUNDS | HOECHST MARION ROUSSEL (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0894805-A1 | Ribose substituted aromatic derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 1999-02-03 | — | — | EP | disclosed |