SCHEMBL6157642

SCHEMBL6157642

CNC(=O)C(=NOC)c1ccccc1C(ON)=C(C)C1CC1c1c(Cl)cccc1Cl

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.30
TSHR P16473 1/20 0.30
SLC9A1 P19634 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156510 0.90 HIF1A (0.38) SLC6A3SLC9A1
SCHEMBL6156363 0.89 SLC9A1 (0.34) SLC9A1
SCHEMBL6156658 0.78 HIF1A (0.39)
SCHEMBL6156654 0.78 HIF1A (0.39)
SCHEMBL467969 0.76 ALDH1A1 (0.39) TSHR
SCHEMBL28685779 0.74 HIF1A (0.33)
SCHEMBL28685781 0.74 HIF1A (0.33)
SCHEMBL7740767 0.70 HIF1A (0.32)
SCHEMBL6156122 0.70 LMNA (0.31)
SCHEMBL5079840 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1286955-B1 ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2005-02-02 EP claimed