Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157278 | 0.97 | MTNR1A (0.39) | MTNR1AMTNR1BALDH1A1LTB4RLTB4R2 | |
| SCHEMBL6156499 | 0.90 | MTNR1A (0.40) | MTNR1AMTNR1BALDH1A1KDM4ELMNA | |
| SCHEMBL6155374 | 0.87 | ADRA2C (0.36) | ALDH1A1LTB4RLTB4R2 | |
| SCHEMBL6156196 | 0.87 | MTNR1A (0.40) | MTNR1AMTNR1BALDH1A1KDM4ELMNA | |
| SCHEMBL6156114 | 0.76 | LTB4R (0.36) | MTNR1AMTNR1BALDH1A1LTB4RLTB4R2 | |
| SCHEMBL6156554 | 0.76 | BCL2 (0.43) | MTNR1AMTNR1BLTB4RLTB4R2 | |
| SCHEMBL6157286 | 0.73 | BCL2 (0.41) | MTNR1AMTNR1BLTB4RLTB4R2 | |
| SCHEMBL6155134 | 0.73 | APP (0.43) | MTNR1AMTNR1B | |
| SCHEMBL6156106 | 0.70 | APP (0.42) | MTNR1AMTNR1B | |
| SCHEMBL6156550 | 0.69 | BCL2 (0.41) | MTNR1AMTNR1BLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |