Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156499 | 0.97 | MTNR1A (0.40) | MTNR1AMTNR1BALDH1A1KDM4ELMNA | |
| SCHEMBL6157278 | 0.90 | MTNR1A (0.39) | MTNR1AMTNR1BALDH1A1KDM4ELMNA | |
| SCHEMBL6156547 | 0.87 | MTNR1A (0.39) | MTNR1AMTNR1BALDH1A1KDM4ELMNA | |
| SCHEMBL6156114 | 0.80 | LTB4R (0.36) | MTNR1AMTNR1BALDH1A1KDM4E | |
| SCHEMBL6156207 | 0.75 | MTNR1A (0.42) | MTNR1AMTNR1B | |
| SCHEMBL6155374 | 0.75 | ADRA2C (0.36) | ALDH1A1 | |
| SCHEMBL6155493 | 0.72 | APP (0.44) | MTNR1AMTNR1B | |
| SCHEMBL6156502 | 0.72 | BCL2 (0.44) | MTNR1AMTNR1B | |
| SCHEMBL6155227 | 0.69 | HTR7 (0.50) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL6155835 | 0.69 | APP (0.44) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |