Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 7/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | IMPDH1 | P20839 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153700 | 1.00 | IMPDH2 (0.47) | IMPDH2ARALDH1A1LRRK2IMPDH1 | |
| SCHEMBL6156911 | 0.79 | IMPDH2 (0.45) | IMPDH2ARALDH1A1IMPDH1KDM4E | |
| SCHEMBL6153703 | 0.79 | IMPDH2 (0.45) | IMPDH2ARALDH1A1IMPDH1KDM4E | |
| SCHEMBL6154412 | 0.76 | SUV39H2 (0.47) | IMPDH2ALDH1A1IMPDH1KDM4EGAA | |
| SCHEMBL6154460 | 0.76 | SUV39H2 (0.47) | IMPDH2ALDH1A1IMPDH1KDM4EGAA | |
| SCHEMBL6154416 | 0.76 | SUV39H2 (0.47) | IMPDH2ALDH1A1IMPDH1KDM4EGAA | |
| SCHEMBL6156003 | 0.74 | DRD2 (0.49) | IMPDH2ARALDH1A1KDM4EGAA | |
| SCHEMBL6156008 | 0.74 | DRD2 (0.49) | IMPDH2ARALDH1A1KDM4EGAA | |
| SCHEMBL6154049 | 0.73 | IMPDH2 (0.41) | IMPDH2ARALDH1A1IMPDH1KDM4E | |
| SCHEMBL6154051 | 0.73 | IMPDH2 (0.41) | IMPDH2ARALDH1A1IMPDH1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| EP-1500643-A1 | BENZAMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182040-A1 | Benzamide derivatives | ROCK1, ROCK2, NHERF1 | IMPDH2 2157/4885AR 1667/4885ALDH1A1 2454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.