Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28685781 | 1.00 | HIF1A (0.33) | HIF1AKMT2AADRA2AMEN1LMNA | |
| SCHEMBL467969 | 0.76 | ALDH1A1 (0.39) | HIF1AKMT2AMEN1LMNAMAPT | |
| SCHEMBL8433381 | 0.76 | KMT2A (0.39) | HIF1AKMT2ACYP2C19MAPTAKR1B1 | |
| SCHEMBL8338404 | 0.76 | KMT2A (0.39) | HIF1AKMT2ACYP2C19MAPTAKR1B1 | |
| SCHEMBL6157642 | 0.74 | SLC6A3 (0.30) | — | |
| SCHEMBL7740767 | 0.72 | HIF1A (0.32) | HIF1A | |
| SCHEMBL7741707 | 0.72 | — | — | |
| SCHEMBL7742005 | 0.71 | LMNA (0.32) | LMNA | |
| SCHEMBL8761028 | 0.70 | SIRT2 (0.38) | HIF1AKMT2AMEN1LMNAHSD17B10 | |
| SCHEMBL13730901 | 0.70 | HIF1A (0.41) | HIF1ALMNAHTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114133382-A | Microbicidal heterocycles | 先正达参股股份有限公司 | 2022-03-04 | — | — | CN | disclosed |