Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27500227 | 0.93 | HTR1D (0.41) | HTR1DHTR1BKCNH2HTR2CPSEN1 | |
| SCHEMBL1016672 | 0.87 | ACHE (0.41) | HTR1DHTR1BPSEN1PSEN2APH1B | |
| SCHEMBL27591540 | 0.79 | HTR2A (0.43) | HTR2CSRD5A1OPRK1DRD2HTR2A | |
| SCHEMBL27493624 | 0.79 | PNMT (0.41) | SRD5A1ADRA2AADRA2BADRA2C | |
| SCHEMBL691836 | 0.75 | PLAU (0.52) | HTR1A | |
| SCHEMBL13929740 | 0.75 | PLAU (0.52) | HTR1A | |
| SCHEMBL29447885 | 0.75 | PLAU (0.52) | HTR1A | |
| SCHEMBL12472685 | 0.75 | DGAT1 (0.48) | MCHR1 | |
| SCHEMBL6952592 | 0.74 | HTR1D (0.50) | HTR1DHTR1BKCNH2HTR2CMCHR1 | |
| SCHEMBL6950353 | 0.74 | OPRK1 (0.62) | HTR1DHTR1BOPRK1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717589-B | For treating or prevent the compound of respiratory syncytial virus disease | 弗·哈夫曼-拉罗切有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-101300244-A | Novel cercosporamide derivative | DAIICHI SANKYO CO LTD (JP) | 2008-11-05 | — | — | CN | disclosed |
| CN-1223561-C | Compound having tetrahydronalphthalene skeleton and liquid crystal compsn. contg. same | DAINIPPON INK & CHEMICALS (JP) | 2005-10-19 | — | — | CN | disclosed |
| CN-1659156-A | Novel guanidinobenzamides | CHIRON CORP (US) | 2005-08-24 | — | — | CN | disclosed |
| EP-1191008-B1 | COMPOUND HAVING TETRAHYDRONAPHTHALENE SKELETON AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DAINIPPON INK & CHEMICALS (JP) | 2005-02-09 | — | — | EP | disclosed |
| US-6746728-B1 | SUPERIOR LIQUID CRYSTALLINITY AND CO-SOLUBILITY WITH CURRENTLY USED LIQUID CRYSTAL COMPOUNDS; TEMPERATURE RANGE OVER WHICH LIQUID CRYSTALLINITY IS SHOWN IS BROAD; THRESHOLD VOLTAGE IS LOW; CAPABLE OF HIGH SPEED RESPONSE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2004-06-08 | — | — | US | disclosed |
| CN-1356969-A | Compound having tetrahydronalphthalene skeleton and liquid crystal compsn. contg. same | DAINIPPON INK & CHEMICALS (JP) | 2002-07-03 | — | — | CN | disclosed |
| EP-1191008-A1 | COMPOUND HAVING TETRAHYDRONAPHTHALENE SKELETON AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-03-27 | — | — | EP | disclosed |