SCHEMBL615767

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL618252	0.88	LMNA (0.39)	ALDH1A1LMNAPDGFRBPDGFRATP53
	SCHEMBL618793	0.88	ALDH1A1 (0.43)	ALDH1A1LMNAPDE10ATUBB4ATUBB
	SCHEMBL618095	0.87	CHEK1 (0.41)	ALDH1A1LMNAPDE10ATP53KDM4E
	SCHEMBL16471515	0.87	MAPK1 (0.36)	CYP1A1CYP1B1ALDH1A1LMNAPDE10A
	SCHEMBL618114	0.87	CYP1A1 (0.43)	CYP1A1CYP1B1ALDH1A1LMNAPDGFRB
	SCHEMBL618801	0.87	PDE10A (0.43)	ALDH1A1LMNAPDE10APOLBKDM4E
	SCHEMBL618973	0.87	KDM4E (0.42)	ALDH1A1LMNATUBB4ATUBBTUBA3C
	SCHEMBL615696	0.86	MGAM (0.46)	ALDH1A1LMNACYP3A4CYP2D6TUBB4A
	SCHEMBL619308	0.86	CYP2D6 (0.43)	ALDH1A1LMNACYP1A2CYP3A4CYP2D6
	SCHEMBL618061	0.85	KMT2A (0.38)	ALDH1A1LMNAPTGS2TUBB1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.